It is a disorder typical of a workaholic ("obsessive about his work") but with a component of anguish for feeling inefficient, that his task does not perform enough. The name comes from the Greek myth of Sisyphus, condemned to roll a large boulder uphill that falls when he reaches the top, so he must climb it again, eternally and futilely. The suffix evokes (in the fantasy of the inventor of the neologism) a disease, which in this case has nothing to do with blood. See Laboradico .
It is said of a new type of disorder, which occurs in a work environment, where obsession, ambition, self-demand and perfectionism, exceed the ability of the sufferer to handle it, which causes discomfort, stress, etc.