The act of knowing oneself involves sequences of integrated brain processes that are initiated by the emerging messages of integrated memories, chronomesically constructed and preserved in a latent way, which are energized by changing their current effectiveness when they are summoned by temporal reality through evocation, imagination or circumstantial memory. These events organically sustain the experiences of the inner or subjective world, which are the biological foundations for introspective analysis, reflection, self-awareness, self-criticism or self-assessment.