Substance of our organism normally present in the blood, which is indicative of our biological state, as our ability to face infections. They can be genetic or acquired, molecular, such as enzymes or proteins, or cellular. Current researchers have identified 5 biomarkers whose high level have been associated with the severity of coronavirus. These are : IL-6 ( interleucine ), D, CRP, LDH and ferritin dimer. This knowledge can help prevent gravity.